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Treatment of NLD is difficult. Sometimes it responds to topical cortisone creams , especially if covered ("occluded") with an airtight dressing. Cortisone injections can also be used to treat NLD. These are more effective than cortisone creams. NLD usually goes through stages of activity and inactivity. One is not able to predict when the condition will flare. Ultraviolet light treatment has been found to control this condition when it is flaring. A baby aspirin each day, and other medications that thin the blood, such as Trental, may help NLD. Other medications, including prednisone pills (steroids) are used in difficult or severe cases.

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Groups of 3 male and 3 female Beagles were given pentoxifylline in doses of 0, 32, 100, 320 or 400 mg/kg/day. There was incoordination, salivation and altered temperament following drug administration. Deaths occurred at doses of 320 and 400 mg/kg due to extensive or focal pulmonary oedema and hemorrhages, and marked congestion in mucosa of the intestinal tract. Acetone was detected in urine at 2 weeks to 26 weeks in some dogs of the 3 highest dose groups. At 52 weeks acetone was no longer detected. Giant cell formation in the testicles was observed in 2 dogs, which died in the 320 mg/kg group. Granuloma in the lymph nodes occurred in 1 dog in the control group, and 2 in the 320 mg/kg group.

Erythromycin ( , Erythrocin), omeprazole ( Prilosec ) and diltiazem ( Cardizem ) increase the concentration of cilostazol by blocking the action of enzymes that destroy cilostazol. Though not specifically studied, a similar interaction could occur with ketoconazole ( Nizoral ), itraconazole ( Sporanox ), fluconazole ( Diflucan ), miconazole ( Monistat ), fluvoxamine ( Luvox ), fluoxetine ( Prozac ), nefazodone ( Serzone ) and sertraline ( Zoloft ). Diltiazem (Cardizem) and omeprazole (Prilosec) also increase concentrations of cilostazol.

What is trental

what is trental

Erythromycin ( , Erythrocin), omeprazole ( Prilosec ) and diltiazem ( Cardizem ) increase the concentration of cilostazol by blocking the action of enzymes that destroy cilostazol. Though not specifically studied, a similar interaction could occur with ketoconazole ( Nizoral ), itraconazole ( Sporanox ), fluconazole ( Diflucan ), miconazole ( Monistat ), fluvoxamine ( Luvox ), fluoxetine ( Prozac ), nefazodone ( Serzone ) and sertraline ( Zoloft ). Diltiazem (Cardizem) and omeprazole (Prilosec) also increase concentrations of cilostazol.

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