Due to its high potency as a corticosteroid, it is available in most countries by prescription only. It should be used in as small a quantity as possible, for as short a period of time as possible. It is not recommended for use in children under 12 years old and should not be used on any open wounds, mucous membranes or the eyes. When using clobetasol propionate, the site at which it is being used, be it the skin or scalp, should not be covered or occluded. The treatment should not be used for a longer period of time than prescribed by the medical practitioner.
Topical steroids like clobetasol gel can be a concern if they are used for a long time. Some patients develop skin thinning, which can expose them to the risk of infection, and discoloration can also appear. The medications can also interfere with the body’s ability to produce corticosteroid hormones internally, which can cause problem when the drug is discontinued. If inflammation doesn’t respond after approximately two weeks of treatment, the patient may need a different medication or more aggressive evaluation to find the underlying cause of the skin irritation. For example, the patient might be experiencing an allergic reaction to something in the environment that hasn’t been eliminated, like a food that hasn’t been identified as an allergen.
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