Propionate gut bacteria

Dr Douglas Morrison, author of the paper from the Scottish Universities Environmental Research Centre at the University of Glasgow, commented: “We developed inulin-propionate ester to investigate the role of propionate produced by the gut microbiota in human health. This study illustrates very nicely that signals produced by the gut microbiota are important for appetite regulation and food choice. This study also sheds new light on how diet, the gut microbiome and health are inextricably linked adding to our understanding of how feeding our gut microbes with dietary fibre is important for healthy living.”

Inulin and FructoOligoSaccharides (FOS) are soluble prebiotic fibers that promote gut and overall health through their fermentation by gut flora to yield important metabolites, including lactic acid and the short chain fatty acids acetate, propionate and butyrate. These metabolites help to maintain proper pH in the gut, discourage the growth of unfriendly bacteria, reduce the absorption of toxic ammonia and positively affect bone health by increasing the bioavailability of dietary calcium.* Moreover, acetate, propionate and butyrate promote the integrity of the intestinal cells lining the colon and promote healthy lipid metabolism.*

This test involved volunteers drinking either a milkshake containing 10 grams of inulin propionate ester, or inulin on its own, which acted as the control. Participants were then strapped to an MRI machine, and shown various pictures of low or high calorie foods. The scans show that those who had the supplement had less activity in the reward regions of their brain—but only when looking at high-calorie foods. They also found that the pictures looked less appealing. The volunteers were then given a bowl of pasta with tomato sauce and told to eat as much as they liked. The supplement group ate 10% less than the control.

Disclaimer: The entire contents of this website are based upon the opinions of Dr. Mercola, unless otherwise noted. Individual articles are based upon the opinions of the respective author, who retains copyright as marked. The information on this website is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge and information from the research and experience of Dr. Mercola and his community. Dr. Mercola encourages you to make your own health care decisions based upon your research and in partnership with a qualified health care professional. If you are pregnant, nursing, taking medication, or have a medical condition, consult your health care professional before using products based on this content.

Propionate gut bacteria

propionate gut bacteria

Disclaimer: The entire contents of this website are based upon the opinions of Dr. Mercola, unless otherwise noted. Individual articles are based upon the opinions of the respective author, who retains copyright as marked. The information on this website is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge and information from the research and experience of Dr. Mercola and his community. Dr. Mercola encourages you to make your own health care decisions based upon your research and in partnership with a qualified health care professional. If you are pregnant, nursing, taking medication, or have a medical condition, consult your health care professional before using products based on this content.

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