While it’s common for bodybuilders to suspect that Anadrol would be an even riskier choice for use by women than most anabolic steroids, actually the reverse is true. Medically, once per day dosing of 50 mg/day over extended periods has shown only a moderate rate of virilization problems . The same certainly cannot be said of Anavar , Dianabol, or Winstrol ( stanozolol .) While not necessarily sufficient for high level female bodybuilding competition by today’s standards, such a dose actually is considerably more than needed by most women for excellent results in adding muscle, losing fat, and generally improving their physiques. Half this dose — 25 mg/day, preferably taken as divided doses — is very effective and is so far as I know the lowest-risk way to obtain this degree of benefit from anabolic steroids.
Although I am usually not inclined to posit speculations on why a particular drug does or doesn't do something, in this case I will. Im guessing that the higher doses of Anadrol cause enough appetite suppression (at least anecdotally) to make eating rather difficult. It can also increase insulin resistance and glucose intolerance (5). This has the effect of making macronutrient absorption more inefficient, and could also be a factor in reducing gains when the dosage goes over 100mgs/day. Unfortunately, Anadrol also has a reasonably profound effect on your body's natural hormonal system, on par with most other oral steroids , but not as bad as most injectables, and its certainly not as harsh on your lipid profile as many anabolics are